Treatment for Severe Depression

Client Testimonials

Here's what our clients say about us

Very professional, was very open to answer questions. Very clean. And it is also nice to have Tracy follow up personally about the procedure. Will definitely be going back!

—  Kyle


Are you suffering from a relentless lack of enjoyment in life? Do you constantly feel down and cannot see the “bright side” of things in life?  If so, you might be struggling with depression. If you have had depression for a long time and tried several antidepressants and other medications and counseling or other behavioral therapies to try and find relief without any or much success you might be suffering from treatment-resistant depression. 

Treatment-resistant depression (TRD) typically refers to an insufficient response to at least two antidepressant trials of adequate doses and duration. TRD is a relatively common occurrence with up to 50% to 60% of the patients not achieving adequate relief following treatment and therapy. Many of these patients have tried therapies consisting of counseling, biofeedback, countless medications, transcranial magnetic stimulation (TMS) and even electroconvulsive therapy (ECT or shock treatment). 

Treatment-resistant depression is most seen with major depressive disorder (MDD); however, it is also seen in the depressed phase of bipolar disorder. More than 30 percent of those suffering from bipolar disorder and receiving treatment do not experience sustained reduction of depressive symptoms. TRD has considerable effects on patients, their families, communities, and society at large. Treatment-resistant depression represents the highest direct and indirect medical costs among those with major depressive disorder. Individuals with TRD are twice as likely to be hospitalized. The cost of this hospitalization is more than six times the average total cost for depressed patients who are not treatment resistant. 

Looking for relief from depression? IV Ketamine therapy may help!

In the last 10 to 15 years, research has consistently shown that low doses of ketamine, administered intravenously, can rapidly relieve depressive symptoms in patients whose depression has been otherwise untreatable.

​Ketamine is recognized as one of the safest, most widely used anesthetics in the world. It is approved for many medical uses in human and veterinary medicine and is commonly used with young children.

World renowned institutions have confirmed the effectiveness of ketamine infusions for the treatment of mood disorders and various pain conditions. Yale University, Stanford University, Harvard University, UCLA, USC, NYU, the National Institute of Mental Health, the Black Dog Institute of Australia, Cleveland Clinic, and Mt. Sinai Hospital are a few of the leaders.

Ketamine is Different from Antidepressants

Antidepressants can take weeks or even months to reach therapeutic levels in your system to have an effect. Even then, some patients try many medications in endless combinations and doses and still feel little or no relief from their depression. Ketamine infusion therapy for depression works quickly to deliver significant relief from symptoms. Many patients see substantial relief within 1-2 days of their 2nd and 3rd infusion. 

Ketamine for depression can deliver relief without some of the unpleasant side effects of antidepressant medications, which can include loss of libido, weight gain, insomnia or sleepiness, nausea, dizziness, fatigue, dry mouth blurred vision, and suicidal ideation.

About Ketamine Therapy at Wyoming Wellness Center

​At Wyoming Wellness Center, we offer the best possible care in our state-of-the-art facility. Our highly experienced, trained, and compassionate team consist of providers who have carefully considered the research and results of IV ketamine infusion therapy. 


Mental health ketamine infusion therapy at Wyoming Wellness Center will start with an initial meeting with our mental health provider. From that meeting, you and our team will develop a plan for the course of care to be provided. If ketamine therapy is determined to be a good treatment option, it will initially consist of 8 infusions:

  • 2 infusions week 1

  • 2 infusions week 2

  • 1 infusion week 3

  • 1 infusion week 4

  • 1st "Booster" week 6

  • 2nd "Booster" week 8

Within this time frame, our team will work with you to monitor the effectiveness of the treatment, provide you with support, and collaborate with your primary mental health provider to assist you in learning skills and meeting your goals. 

After your initial 8 infusions you will come back for "Booster" infusions on an as needed basis, based upon your symptoms and mood. Usually that is every 4-6 weeks but it may be less often based on your individual mood and symptoms. 

Our staff at Wyoming Wellness Center recognize that every patient is unique and that individual responses to ketamine infusions will vary. Therefore, we will tailor your treatment course to you and your body’s needs. Your individual symptoms, needs, and goals of care will determine your course of treatment.

When you undergo ketamine therapy at Wyoming Wellness Center you are closely monitored by our highly experienced providers and nurses. We use hospital grade equipment to monitor all your vital signs, just like an ICU setting. You will be kept safe, in a comfortable, quiet, and relaxing environment. 

Some patients experience short-term dizziness, nausea, and fatigue, but these sensations usually disappear rapidly. After 50 years of ketamine being administered at much higher doses, and approximately 10+ years of research on ketamine treatment for mood and pain disorders, there have been no long-term side effects noted at these low doses.

Following your initial treatment series, we will follow up with you, your primary care provider and your mental health provider to monitor your depressive symptoms, ensure your mental health counseling is progressing well and determine your need for maintenance infusions.

​Over the last 10+ years, ketamine has been used successfully in treating mental health and chronic pain disorders.  However, because it is not approved by the FDA for this secondary use, almost all insurance companies will not pay for ketamine infusion therapy. For that reason, we do not bill insurance companies. We will provide you with statements and the necessary billing codes, in the form of a superbill, for you to file a claim, if you desire to do so, and request a superbill from us.

If you or someone you love is in the grip of ongoing depression, ketamine treatment for mood disorders may help.

For further information you can also check out the links below:


Ketamine Advocacy Network

Substance Abuse and Mental Health Services Administration (SAMHSA)

Rapidly Acting Treatments for Treatment-Resistant Depression (RAPID)